Acetone → 6-[4,5-Bis(4-fluorophenyl)-2-propan-2-ylimidazol-1-yl]-4-hydroxyhex-5-en-2-one
Reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:11][C:12]([CH3:13])=[O:14].[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[F:15][c:16]1[cH:17][cH:18][c:19](-[c:22]2[n:23][c:24]([CH:38]([CH3:39])[CH3:40])[n:25]([CH:34]=[CH:35][CH:36]=[O:37])[c:26]2-[c:27]2[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]2)[cH:20][cH:21]1.[Li+:10]>>[CH2:11]([C:12]([CH3:13])=[O:14])[CH:36]([CH:35]=[CH:34][n:25]1[c:24]([CH:38]([CH3:39])[CH3:40])[n:23][c:22](-[c:19]2[cH:18][cH:17][c:16]([F:15])[cH:21][cH:20]2)[c:26]1-[c:27]1[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]1)[OH:37]Participants
6
Sources & evidence
- ORD record
- ord-bbc950093df44e91a4baae112b589c4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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