Toluene → rac-(4S*,5R*)-2-(4-Bromo-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole
Reaction equation
[CH2:39]([O:40][C:41](=[O:42])[c:43]1[cH:44][cH:45][c:46]([Br:49])[cH:47][c:48]1[O:50][CH2:51][CH3:52])[CH3:53].[CH3:35][Al:36]([CH3:37])[CH3:38].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[CH3:60][c:61]1[cH:62][cH:63][cH:64][cH:65][cH:66]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([CH3:34])[N:9]=[C:10]([c:21]3[c:22]([O:31][CH2:32][CH3:33])[cH:23][c:24]([C:27]([CH3:28])([CH3:29])[CH3:30])[cH:25][cH:26]3)[NH:11][C:12]2([CH3:13])[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([CH3:34])[N:9]=[C:10]([c:21]3[c:22]([O:31][CH2:32][CH3:33])[cH:23][c:24]([Br:49])[cH:25][cH:26]3)[NH:11][C:12]2([CH3:13])[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e6c6bec44dc44eac9c5db74f9a6f4f6d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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