Diethyl Ether → 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2,3-diphenylpropan-1-amine

HRID 696642Notes

Reaction equation

HRID 696642 reaction equation
[Al+3:35].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:40][CH2:41][O:42][CH2:43][CH3:44].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([CH:17]([CH:18]([C:19](=[O:20])[NH2:21])[c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1.[H-:34].[H-:37].[H-:38].[H-:39].[Li+:36]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([CH:17]([CH:18]([CH2:19][NH2:21])[c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 687038113-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2,3-diphenylpropanamide

Product 1

HCID 687029583-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2,3-diphenylpropan-1-amine

Sources & evidence

ORD record
ord-3b752aeb9c4346e4b046ff8382e40f73
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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