Methanol → 2-chloro-5-[3-[1-(2-toluoylmethyl)-2-oxo-5-pivaloyl-8-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl]ureido]benzoic acid
Reaction equation
[CH3:53][OH:54].[Li+:47].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1.[OH-:46].[OH2:45].[c:1]1([CH3:44])[c:2]([C:7](=[O:8])[CH2:9][N:10]2[C:11](=[O:43])[CH:12]([NH:28][C:29](=[O:30])[NH:31][c:32]3[cH:33][c:34]([C:39](=[O:40])[O:41][CH3:42])[c:35]([Cl:38])[cH:36][cH:37]3)[CH2:13][N:14]([C:22]([C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[c:15]3[c:16]2[cH:17][c:18]([CH3:21])[cH:19][cH:20]3)[cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH3:44])[c:2]([C:7](=[O:8])[CH2:9][N:10]2[C:11](=[O:43])[CH:12]([NH:28][C:29](=[O:30])[NH:31][c:32]3[cH:33][c:34]([C:39](=[O:40])[OH:41])[c:35]([Cl:38])[cH:36][cH:37]3)[CH2:13][N:14]([C:22]([C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[c:15]3[c:16]2[cH:17][c:18]([CH3:21])[cH:19][cH:20]3)[cH:3][cH:4][cH:5][cH:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b7aac538c7074e5bb4ea64fc2f856b07
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…