Dimethylformamide → 4-(2-Fluorophenyl)-6-methyl-2-morpholin-4-yl-pyrimidine-5-carboxylic acid benzyl-isopropyl-amide
Reaction equation
[CH2:30]([c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)[NH:37][CH:38]([CH3:39])[CH3:40].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:41][CH2:42][Cl:43].[F:7][c:8]1[c:9](-[c:14]2[n:15][c:16]([N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[n:17][c:18]([CH3:23])[c:19]2[C:20](=[O:21])[OH:22])[cH:10][cH:11][cH:12][cH:13]1.[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[F:7][c:8]1[c:9](-[c:14]2[n:15][c:16]([N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[n:17][c:18]([CH3:23])[c:19]2[C:20](=[O:21])[N:37]([CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH:38]([CH3:39])[CH3:40])[cH:10][cH:11][cH:12][cH:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-caa655c2ea5a40458416ef5383c8e9ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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