Hydrochloric Acid → 2-(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-N-(4-methoxy-benzyl)-acetamide

HRID 698046Notes

Reaction equation

HRID 698046 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][c:9]1[n:10][cH:11][c:12]([CH2:23][C:24]([NH:25][CH2:26][c:27]2[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)=[O:35])[c:13]2[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]12)([CH3:5])([CH3:6])[CH3:36].[CH3:38][CH2:39][OH:40].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[ClH:37].[O:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1>>[NH2:7][CH2:8][c:9]1[n:10][cH:11][c:12]([CH2:23][C:24]([NH:25][CH2:26][c:27]2[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)=[O:35])[c:13]2[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]12

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 702EthanolHCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 59341099{6,7-Dimethoxy-4-[(4-methoxy-benzylcarbamoyl)-methyl]-isoquinolin-1-ylmethyl}-carbamic acid tert-butyl ester

Product 1

HCID 468473662-(1-Aminomethyl-6,7-dimethoxy-isoquinolin-4-yl)-N-(4-methoxy-benzyl)-acetamide

Sources & evidence

ORD record
ord-5a93d21e547a486182c33d03b2370647
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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