Tetrahydrofuran → 1-[(5-Bromothiophen-2-yl)methyl]piperidine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:7]=[O:8])[s:6]1.[CH2:15]([Sn:16]([Cl:17])([Cl:18])[CH2:19][CH2:20][CH2:21][CH3:22])[CH2:23][CH2:24][CH3:25].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH2:9]1[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]1.[c:26]1([SiH3:27])[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][N:12]2[CH2:11][CH2:10][CH2:9][CH2:14][CH2:13]2)[s:6]1Participants
6
Sources & evidence
- ORD record
- ord-d84dd43044a7418b8a9e4f52b095250d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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