Hydrochloric Acid → 5-(2-Hydroxy-ethyl)-benzofuran-2-carboxylic acid (2-amino-phenyl)-amide

HRID 698404Notes

Reaction equation

HRID 698404 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:14][C:15](=[O:16])[c:17]2[o:18][c:19]3[c:20]([cH:21]2)[cH:22][c:23]([CH2:26][CH2:27][OH:28])[cH:24][cH:25]3)[cH:10][cH:11][cH:12][cH:13]1)([CH3:5])([CH3:6])[CH3:29].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[ClH:30].[O:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1>>[NH2:7][c:8]1[c:9]([NH:14][C:15](=[O:16])[c:17]2[o:18][c:19]3[c:20]([cH:21]2)[cH:22][c:23]([CH2:26][CH2:27][OH:28])[cH:24][cH:25]3)[cH:10][cH:11][cH:12][cH:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 312751,4-DioxaneHCID 69487867(2-{[5-(2-Hydroxy-ethyl)-benzofuran-2-carbonyl]-amino}-phenyl)-carbamic acid tert-butyl ester

Product 1

HCID 104472675-(2-Hydroxy-ethyl)-benzofuran-2-carboxylic acid (2-amino-phenyl)-amide

Sources & evidence

ORD record
ord-887e2de67b3d406b80cc757b05d0e02e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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