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HRID69842

反应详情

EQUATION

反应方程式

HRID 69842 的结构方程式

REACTANTS

反应物

2
结构：O=C(c1ccccc1)c1ccc(Cl)c([N+](=O)[O-])c1
HCID41743

Benzophenone, 4-chloro-3-nitro-

C13H8ClNO3

结构：CC(C)(C)OC(=O)NC1CCNCC1
HCID723833

4-(N-Boc-amino)piperidine

C10H20N2O2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccc(C(=O)c3ccccc3)cc2[N+](=O)[O-])CC1
HCID60507461

未命名化合物

收率 95%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN1CCCC1=O
溶剂HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

PROCEDURE

实验过程

Method 1 was followed using 4-chloro-3-nitrobenzophenone (1.0 eq), 4-(N-Boc-amino) piperidine (1.1 eq), and TEA (2.0 eq) in NMP yielding tert-butyl 1-(4-benzoyl-2-nitro phenyl)piperidin-4-ylcarbamate (95%). LCMS (m/z): 426.2 (MH+); LC Rt=3.46 min.