Ethyl Acetate → tert-butyl 4-(7-acetyloxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate

HRID 698692Notes

Reaction equation

HRID 698692 reaction equation
[C:1]([CH3:2])(=[O:3])[O:4][CH:5]1[CH2:6][CH:7]([CH3:15])[c:8]2[c:9]1[n:10][cH:11][n:12][c:13]2[Cl:14].[CH3:16][CH:17]1[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH2:21][NH:22]1.[CH3:30][N:31]1[CH2:32][CH2:33][CH2:34][C:35]1=[O:36].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42]>>[C:1]([CH3:2])(=[O:3])[O:4][CH:5]1[CH2:6][CH:7]([CH3:15])[c:8]2[c:9]1[n:10][cH:11][n:12][c:13]2[N:22]1[CH:17]([CH3:16])[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH2:21]1

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 13387N-methyl-2-pyrrolidoneHCID 2756810tert-Butyl 3-methylpiperazine-1-carboxylateHCID 87076585(4-chloro-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-yl) acetate

Product 1

HCID 67143529tert-butyl 4-(7-acetyloxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-2467dc68223e4f68b59d52a136850f48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…