Potassium Cation → 2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-iodo-6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-N-methyl-isobutyramide
Reaction equation
[CH3:35][Si:36]([N-:37][Si:38]([CH3:39])([CH3:40])[CH3:41])([CH3:42])[CH3:43].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[NH:16][c:17]2[cH:18][n:19][c:20]([N:24]3[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]3)[cH:21][c:22]2[I:23])([CH3:31])[CH3:32])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:33])[F:34].[I:45][CH3:46].[K+:44].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([c:17]2[cH:18][n:19][c:20]([N:24]3[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]3)[cH:21][c:22]2[I:23])[CH3:35])([CH3:31])[CH3:32])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:33])[F:34]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-26ca6828fc024c7386a7126c93612d0d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…