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HRID69949

反应详情

EQUATION

反应方程式

HRID 69949 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
HCID90495

Di-tert-butyl dicarbonate

C10H18O5

结构：Nc1cc(Cl)nc(C(F)(F)F)n1
HCID245271

6-Chloro-2-(trifluoromethyl)pyrimidin-4-amine

C5H3ClF3N3

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)Nc1cc(Cl)nc(C(F)(F)F)n1
HCID87669774

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

PROCEDURE

实验过程

Method 24 was followed using 6-chloro-2-(trifluoromethyl)pyrimidin-4-amine (1.0 equiv.), BOC2O (1.0 equiv.), and DMAP (cat.) to afford tert-butyl 6-chloro-2-(trifluoromethyl)pyrimidin-4-ylcarbamate in 64%. LCMS (m/z): 298.1 (MH+); LC Rt=4.73 min.