Dimethylformamide → 4-chloro-N-(6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-5-methylpicolinamide

HRID 699672Notes

Reaction equation

HRID 699672 reaction equation
[CH3:51][N:52]1[CH2:53][CH2:54][O:55][CH2:56][CH2:57]1.[CH3:58][N:59]([CH3:60])[CH:61]=[O:62].[CH:12]1([n:15]2[c:16](-[c:20]3[cH:21][cH:22][cH:23][c:24]([NH2:26])[n:25]3)[n:17][n:18][cH:19]2)[CH2:13][CH2:14]1.[Cl:1][c:2]1[cH:3][c:4]([C:9](=[O:10])[OH:11])[n:5][cH:6][c:7]1[CH3:8].[P-:27]([F:28])([F:29])([F:30])([F:31])([F:32])[F:33].[n:34]1([O:35][C:36]([N:37]([CH3:38])[CH3:39])=[N+:40]([CH3:41])[CH3:42])[c:43]2[n:44][cH:45][cH:46][cH:47][c:48]2[n:49][n:50]1>>[Cl:1][c:2]1[cH:3][c:4]([C:9](=[O:11])[NH:26][c:24]2[cH:23][cH:22][cH:21][c:20](-[c:16]3[n:15]([CH:12]4[CH2:13][CH2:14]4)[cH:19][n:18][n:17]3)[n:25]2)[n:5][cH:6][c:7]1[CH3:8]

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 534400144-Chloro-5-methylpyridine-2-carboxylic acidHCID 581029666-(4-Cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine

Product 1

HCID 581029954-chloro-N-(6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-5-methylpicolinamide

Sources & evidence

ORD record
ord-89c14dfdc4ea4e39bcfe7fb420648650
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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