Dimethylformamide → 2,2,2-Trifluoro-N-[1-(4-{7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-3-methoxy-phenyl)-cyclobutyl]-acetamide
Reaction equation
[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[CH:28]([N:29]([CH2:30][CH3:31])[CH:32]([CH3:33])[CH3:34])([CH3:35])[CH3:36].[NH2:37][c:38]1[c:39]([O:55][CH3:56])[cH:40][c:41]([C:44]2([NH:48][C:49]([C:50]([F:51])([F:52])[F:53])=[O:54])[CH2:45][CH2:46][CH2:47]2)[cH:42][cH:43]1.[OH:1][c:2]1[n:3][n:4]2[c:5]([cH:6][n:7]1)[cH:8][cH:9][c:10]2-[c:11]1[c:12]([N:17]([S:18](=[O:19])(=[O:20])[CH3:21])[CH3:22])[cH:13][cH:14][cH:15][cH:16]1>>[c:2]1([NH:37][c:38]2[c:39]([O:55][CH3:56])[cH:40][c:41]([C:44]3([NH:48][C:49]([C:50]([F:51])([F:52])[F:53])=[O:54])[CH2:45][CH2:46][CH2:47]3)[cH:42][cH:43]2)[n:3][n:4]2[c:5]([cH:6][n:7]1)[cH:8][cH:9][c:10]2-[c:11]1[c:12]([N:17]([S:18](=[O:19])(=[O:20])[CH3:21])[CH3:22])[cH:13][cH:14][cH:15][cH:16]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e251d6590839421c972bf2f1e2e1f3b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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