Water → 2-(3-Chloropropyl)-4,4-dimethyl-1,2,3,4-tetrahydro 1isoquinolinone
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:6][C:7]1([CH3:18])[CH2:8][NH:9][C:10](=[O:17])[c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]21.[Cl:19][CH2:20][CH2:21][CH2:22][Br:23].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[OH2:24]>>[CH3:6][C:7]1([CH3:18])[CH2:8][N:9]([CH2:22][CH2:21][CH2:20][Cl:19])[C:10](=[O:17])[c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]21Participants
6
Sources & evidence
- ORD record
- ord-e903b0004eeb4696ab365e14ed7c54c2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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