Sodium ion → 3-(2,6-difluoro-3,5-dimethoxy-phenyl)-1-ethyl-7-methylsulfanyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one
Reaction equation
[C:28](=[O:29])([n:30]1[cH:31][cH:32][n:33][cH:34]1)[n:35]1[cH:36][cH:37][n:38][cH:39]1.[F:1][c:2]1[c:3]([NH:13][CH2:14][c:15]2[c:16]([NH:23][CH2:24][CH3:25])[n:17][c:18]([S:21][CH3:22])[n:19][cH:20]2)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9].[H-:26].[Na+:27].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[F:1][c:2]1[c:3]([N:13]2[CH2:14][c:15]3[c:16]([n:17][c:18]([S:21][CH3:22])[n:19][cH:20]3)[N:23]([CH2:24][CH3:25])[C:28]2=[O:29])[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b21f4a5f12ea4eaebb276bc5f4379961
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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