反应详情

4-Allylphenol, (6.14 g, 0.046 moles), 4-methoxybenzyl chloride, (6.3 ml, 0.046 moles), potassium carbonate (8.3 g, 0.06 moles) and a catalytic amount of potassium iodide were mixed together in about 200 ml acetone, and heated to reflux, with stirring. The reaction was allowed to proceed overnight, then cooled to room temperature and diluted with about 100 ml water. The product was extracted into ethyl acetate (3 times, 300 ml each time), and then dried over magnesium sulfate/potassium carbonate, filtered and concentrated in vacuo to yield the title compound as a light yellow solid, m.p. 59-61° C.

1. temperatureheated
2. temperatureto reflux
3. extractionThe product was extracted into ethyl acetate (3 times, 300 ml each time)
4. dry with materialdried over magnesium sulfate/potassium carbonate
5. filtrationfiltered
6. concentrationconcentrated in vacuo