反应详情

Working as described in Example 3 but replacing 2-[2-chloroethyl]-6,7-dimethoxy-1(2H)-phthalazinone with an equivalent amount of 2-(2-chloroethyl)-7-nitro-1(2H)-phthalazinone and replacing N-phenyl piperazine with an equivalent amount of 4-(4-fluorobenzoyl)-piperidine, 2-{2-[4-(4-fluorobenzoyl)-piperidin-1-yl]-ethyl}-7-nitro-1-(2H)-phthalazinone hydrochloride is obtained (m.p. 280°-285° C., from ethyl alcohol).