Benzyl mercaptan → HCID 86690991, compound

HRID 70430Notes

Reaction equation

HRID 70430 reaction equation
Br[C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][C:8]2=[O:11])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[C:15]1([CH2:21][SH:22])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[CH2:21]([S:22][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][C:8]2=[O:11])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 3

HCID 7509Benzyl mercaptanHCID 11430Potassium CarbonateHCID 100609406-bromo-5-nitro-2,3-dihydro-1H-inden-1-one

Product 1

HCID 86690991HCID 86690991, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following General Procedure A, the title compound (672 mg, 79%) was prepared from 6-bromo-5-nitro-2,3-dihydro-1H-inden-1-one (1.5 g, 5.86 mmol), phenylmethanethiol (1 ml, 8.79 mmol) and K2CO3 (4.0 g, 29.29 mmol) in DMF (20 ml).

Sources & evidence

ORD record
ord-6894ae1ee5c54a259c240242f1316eaf
Source dataset
uspto-grants-2014_09
Patent number
US08822530B2

Reaction notes

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