Hydrochloric Acid → HCID 20074096, compound

HRID 704405Notes

Reaction equation

HRID 704405 reaction equation
C([NH:6][CH2:7][CH2:8][NH:9][CH2:10][CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(OCC)=O.[ClH:19]>>[ClH:19].[ClH:19].[C:13]1([CH2:12][CH2:11][CH2:10][NH:9][CH2:8][CH2:7][NH2:6])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20074095HCID 20074095, compound

Product 1

HCID 20074096HCID 20074096, compound

Procedure

A solution of 580 mg of N-carboethoxy-N'-(3-phenylpropyl)ethylenediamine in 10 ml of concentrated hydrochloric acid was heated in a sealed tube at 120° C. overnight. The mixture was concentrated under reduced pressure. Toluene was added and the mixture was again concentrated. Two repetitions of this procedure gave 630 mg of N-(3-phenylpropyl)ethylenediamine dihydrochloride. This product was submitted to the next step without purification.

Workup

  1. concentrationThe mixture was concentrated under reduced pressure
  2. additionToluene was added
  3. concentrationthe mixture was again concentrated

Sources & evidence

ORD record
ord-d4be1628ec3a488fab82d2e90993a73a
Source dataset
uspto-grants-1991_01
Patent number
US04987132

Reaction notes

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