反应详情

47.2 g (0.2 mol) of ethyl 1-(bromoacetyl)-cyclopropanecarboxylate are added to a suspension of b 28 g (0.2 mol) of potassium carbonate and 26 g (0.2 mol) of 4-chlorophenol in 300 ml of acetone and the mixture is heated under reflux for 6 hours. Inorganic salts are then filtered off, the filtrate is concentrated under reduced pressure and the residue is distilled in vacuo. 39 g (69% of theory) of ethyl 1-(4-chlorophenoxyacetyl)-cyclopropanecarboxylate are obtained. B.P. 148°-150° C./0.45 mbar.

1. temperaturethe mixture is heated
2. temperatureunder reflux for 6 hours
3. filtrationInorganic salts are then filtered off
4. concentrationthe filtrate is concentrated under reduced pressure
5. distillationthe residue is distilled in vacuo