4-Hydroxybenzaldehyde → Beta-Nitrostyrene
Reaction equation
O[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[N+:10]([CH3:13])([O-:12])=[O:11]>>[N+:10]([CH:13]=[CH:6][C:5]1[CH:8]=[CH:9][CH:2]=[CH:3][CH:4]=1)([O-:12])=[O:11]Participants
3
Reactant 2
Product 1
Procedure
In the present application, the Henry reaction between p-hydroxy benzaldehyde and nitromethane at 90° C. was carried out, resulting in the formation of nitrostyrene. Typically, 20 mg of a particular aminofunctionalized mesoporous sample was added into a mixture of 122 mg (1 mmol) p-hydroxybenzaldehyde and 10 mL of nitromethane. The reaction mixture was stirred at 90° C. under nitrogen and aliquots of the reaction product were taken with a filter syringe and characterized by solution 1H NMR spectroscopy and GC-MS over the course of the reactions. The percent yield and conversion were determined by using 1H NMR spectra measured in deutrated acetone.
Sources & evidence
- ORD record
- ord-58a6a08eb409458dacd94fc1f3a7aa15
- Source dataset
- uspto-grants-2015_11
- Patent number
- US09174203B2
Reaction notes
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