Selenium Dioxide → 4-Bromo-2,1,3-benzoselenadiazole

HRID 70751Notes

Reaction equation

HRID 70751 reaction equation
[Br:1][C:2]1[C:3]([NH2:9])=[C:4]([NH2:8])[CH:5]=[CH:6][CH:7]=1.[Se:10](=O)=O>C(O)C.O>[Br:1][C:2]1[C:3]2[C:4](=[N:8][Se:10][N:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 24007Selenium DioxideHCID 124898393-Bromobenzene-1,2-diamine

Product 1

HCID 711501924-Bromo-2,1,3-benzoselenadiazole

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

The specific preparation is described as follows: refluxing 3-bromo-1,2-diaminobenzene in ethanol solution, then adding into selenium dioxide dissolved in hot water, after that, refluxing for 2 hours. The precipitation is recrystallized with ethyl acetate after being filtered to get 4-bromo-2,1,3-benzoselenadiazole finally.

Workup

  1. customThe specific preparation
  2. temperatureafter that, refluxing for 2 hours
  3. customThe precipitation
  4. customis recrystallized with ethyl acetate
  5. filtrationafter being filtered

Sources & evidence

ORD record
ord-7150227821db4b80bc2389f71b850cfe
Source dataset
uspto-grants-2014_09
Patent number
US08822634B2

Reaction notes

Loading…