HCID 86729487, compound → HCID 68539279, compound

HRID 712443Notes

Reaction equation

HRID 712443 reaction equation
C([N:8]1[CH2:12][CH:11]2[CH2:13][CH2:14][O:15][CH2:16][CH:10]2[CH2:9]1)C1C=CC=CC=1>CCO.[OH-].[OH-].[Pd+2]>[CH2:12]1[NH:8][CH2:9][CH:10]2[CH2:16][O:15][CH2:14][CH2:13][CH:11]12

Participants

4

Reactant 1

HCID 86729487HCID 86729487, compound

Product 1

HCID 68539279HCID 68539279, compoundYield 53.2%

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 702EthanolSolvent

Procedure

To a solution of 2-benzyloctahydropyrano[3,4-c]pyrrole (0.45 g) in EtOH (30 mL) was added 20% Pd(OH)2 (0.30 g). The suspension was stirred under H2 for 12 h and filtered. The filtrate was concentrated in vacuo to give the title compound (0.14 g). The compound was characterized by the following spectroscopic data: MS (ESI, pos. ion) m/z: 128.3 (M+1).

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-b58a8a70399d4663bf32285064d66fcd
Source dataset
uspto-grants-2015_11
Patent number
US09181277B2

Reaction notes

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