反应详情

To a solution of 6-allyl-6-phenyl-1,4-dioxaspiro[4.5]decane (444 mg, 1.719 mmol) in THF (5 mL) was added a solution of sodium periodate (441 mg, 2.062 mmol) in water (5.00 mL), and 0.175 ml of 2.5% OsO4 in t-BuOH, and the mixture was stirred for 3 hrs. At the end of the stirring it was added to EtOAc and washed with water, aq. Na2S2O3 and brine. It was dried over Na2SO4 and evaporated to give an oily residue.

1. washwashed with water, aq. Na2S2O3 and brine
2. dry with materialIt was dried over Na2SO4
3. customevaporated
4. customto give an oily residue