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HRID712863

反应详情

EQUATION

反应方程式

HRID 712863 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：N#Cc1ccc(CBr)cc1
HCID86996

Benzonitrile, 4-(bromomethyl)-

C8H6BrN

结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3)CC2)cc1
HCID71204684

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(C#N)cc3)CC2)cc1
HCID71204686

未命名化合物

收率 74.6%

PROCEDURE

实验过程

The title compound (D121) (35 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from (R)-methyl 4-(1-(piperidine-2-carboxamido)cyclopropyl)benzoate (D87) (34 mg) and 4-Cyanobenzylbromide (33 mg). (Na2CO3: 4 eq; reaction time: 18 hrs; 68° C.)