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HRID712898

反应详情

EQUATION

反应方程式

HRID 712898 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(C(F)(F)F)cc3)CC2)cc1
HCID71204731

未命名化合物

PRODUCTS

生成物

1
结构：O=C([O-])c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(C(F)(F)F)cc3)CC2)cc1.[Li+]
HCID71502400

未命名化合物

PROCEDURE

实验过程

The title compound (E4) (50 mg) was prepared according to the general procedure for esters hydrolysis (Method A) starting from (R)-methyl 4-(1-(1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxamido)cyclopropyl)benzoate (D119) (74 mg). (LiOH: 3 eq; Reaction time: 3 hrs; RT)