HCID 67972043, compound → HCID 66692371, compound

HRID 713712Notes

Reaction equation

HRID 713712 reaction equation
[N:1]1([CH:6]2[CH:11]3[CH:7]2[CH2:8][N:9](C(OC(C)(C)C)=O)[CH2:10]3)[CH:5]=[N:4][N:3]=[N:2]1>Cl.O1CCOCC1>[N:1]1([CH:6]2[CH:7]3[CH:11]2[CH2:10][NH:9][CH2:8]3)[CH:5]=[N:4][N:3]=[N:2]1

Participants

4

Reactant 1

HCID 67972043HCID 67972043, compound

Product 1

HCID 66692371HCID 66692371, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 312751,4-DioxaneSolvent

Procedure

The title compound from Step A above (2.6 g, 12.2 mmol) was dissolved in 4 M HCl in dioxane (200 mL) and stirred at RT overnight. The product was concentrated under reduced pressure and dried under high vacuum to give 6-(1H-tetrazol-1-yl)-3-azabicyclo[3.1.0]hexane. ESI-MS calculated for C6H9N5: Exact Mass: 151.09. Found 152.05.

Workup

  1. concentrationThe product was concentrated under reduced pressure
  2. customdried under high vacuum

Sources & evidence

ORD record
ord-ad0b47ab09d1410b9fa56903969b1d1a
Source dataset
uspto-grants-2015_11
Patent number
US09186354B2

Reaction notes

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