反应详情

In analogy to the procedure described for the preparation of example 8, (rac)-4-(8-amino-5,6,7,8-tetrahydroisoquinolin-4-yl)benzonitrile (example 1) was reacted with isobutyryl chloride to give the title compound as a off-white powder in 63% yield. MS: 320.2 (M+H+).