反应详情

To a solution of 6-allyl-6-phenyl-1,4-dioxaspiro[4.5]decane (444 mg, 1.719 mmol) in THF (5 mL) was added a solution of sodium periodate (441 mg, 2.062 mmol) in water (5.00 mL), and 0.175 ml of 2.5% OsO4 in t-BuOH, and the mixture was stirred for 3 hrs. Next, the stirring was stopped and the mixture was added to EtOAc and washed with water, aq. Na2S2O3, and brine. The resulting material was dried over Na2SO4 and evaporated to give an oily residue.

1. washwashed with water, aq. Na2S2O3, and brine
2. dry with materialThe resulting material was dried over Na2SO4
3. customevaporated
4. customto give an oily residue