反应详情

温度

2.5 °C

Cyclohexanecarboximidamide (100 mg, 792 μmol) and DIPEA (512 mg, 3.96 mmol) in 10 mL DCM at 0-5° C. were treated with perchloromethyl mercaptan (147 mg, 792 μmol) in 5 mL DCM and stirred for 1 hr at 0-5° C. The mixture was concentrated in vacuo to give a brown solid which was used with out further purification in the subsequent step.

1. concentrationThe mixture was concentrated in vacuo
2. customto give a brown solid which
3. customwas used with out further purification in the subsequent step