反应详情

To a solution of ethyl(5-(((benzyloxy)carbonyl)amino)pyridin-2-yl)acetate (1.0 g) obtained in Step A of Example 363 in a mixed solvent of tetrahydrofuran (20 mL) and 2-propanol (5.0 mL) was added 2 M aqueous sodium hydroxide solution (6.4 mL) in an ice bath, and the mixture was stirred at the same temperature for 3 hr. The reaction mixture was collected by filtration to give the title compound (2.6 g).

1. filtrationThe reaction mixture was collected by filtration