Dodecylamine → HCID 62291629, compound

HRID 715478Notes

Reaction equation

HRID 715478 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:16][N:17]2C(=O)C3C(=CC=CC=3)C2=O)[CH:5]=[N:6][C:7]=1[O:8][CH2:9][C:10]([F:15])([F:14])[CH:11]([F:13])[F:12].CCCCCCCCCCCCN>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:16][NH2:17])[CH:5]=[N:6][C:7]=1[O:8][CH2:9][C:10]([F:14])([F:15])[CH:11]([F:12])[F:13]

Participants

3

Reactant 2

HCID 13583DodecylamineHCID 89874509HCID 89874509, compound

Product 1

HCID 62291629HCID 62291629, compoundYield 87%

Procedure

The title compound is prepared in 87% yield (947 mg, colorless oil) from 2-((5-chloro-6-(2,2,3,3-tetrafluoropropoxy)pyridin-3-yl)methyl)isoindoline-1,3-dione (1.61 g, 4.00 mmol, Step-2) in a similar manner to Step-5 of Amine-12.

Sources & evidence

ORD record
ord-d2829c2d0caf47faac6bdffc751e8e75
Source dataset
uspto-grants-2015_11
Patent number
US09187475B2

Reaction notes

Loading…