反应详情

温度

80 °C

The mixture consisting of 1.62 g of 2,5-difluoronitrobenzene, 1.9 g of nipecotamide and 10 ml of NMP was heated with stirring to 80° C. for 2 hours. After the mixture had been allowed to cool, 30 ml of water were added and the mixture was stirred at RT for 30 minutes. The precipitated solid was filtered off with suction and dried under reduced pressure.

1. temperaturewas heated
2. temperatureto cool
3. stirringthe mixture was stirred at RT for 30 minutes
4. filtrationThe precipitated solid was filtered off with suction
5. customdried under reduced pressure