Oxalyl chloride → 2-Fluoro-5-nitrobenzoyl chloride

HRID 722553Notes

Reaction equation

HRID 722553 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4](O)=[O:5].C(Cl)(=O)C([Cl:17])=O>>[F:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([Cl:17])=[O:5]

Participants

3

Reactant 2

HCID 65578Oxalyl chlorideHCID 2809972-Fluoro-5-nitrobenzoic acid

Product 1

HCID 109765702-Fluoro-5-nitrobenzoyl chloride

Procedure

Prepared by then method of Example 15a), from 2-fluoro-5-nitrobenzoic acid (2.0 g, 11.0 mmol) and oxalyl chloride (2.89 ml, 33.0 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.

Sources & evidence

ORD record
ord-8fca0ace76a64af6880e1d947ff249e0
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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