反应详情

A solution of 1-[4-(2-bromoethoxy)phenyl]-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one (50 mg) in acetonitrile (1 ml) was left to stand with methylamine (1M in THF, 1 ml) and sodium iodide (5 mg) and 24 hours. The reaction solution was filtered and concentrated. The residue was purified by preparative HPLC. The product with the molecular weight of 401.47 (C24H23N3O3); MS (ESI): 402 ([M+H]+), was obtained as hydroformate in this way.

1. filtrationThe reaction solution was filtered
2. concentrationconcentrated
3. customThe residue was purified by preparative HPLC
4. customMS (ESI): 402 ([M+H]+), was obtained as hydroformate in this way