Sodium Iodide → HCID 15956309, compound

HRID 724936Notes

Reaction equation

N[C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]2[CH:29]=[N:28][C:13]3[N:14]([CH2:26][CH3:27])[C:15]4[N:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:16]=4[N:17]([CH3:20])[C:18](=[O:19])[C:12]=3[CH:11]=2)[CH:5]=[CH:6][CH:7]=1.[I-:30].[Na+]>>[Cl:25][C:23]1[CH:22]=[CH:21][C:16]2[N:17]([CH3:20])[C:18](=[O:19])[C:12]3[CH:11]=[C:10]([CH2:9][CH2:8][C:4]4[CH:5]=[CH:6][CH:7]=[C:2]([I:30])[CH:3]=4)[CH:29]=[N:28][C:13]=3[N:14]([CH2:26][CH3:27])[C:15]=2[N:24]=1

Participants

Reactant 2

HCID 5238Sodium Iodide

HCID 470757HCID 470757, compound

Product 1

HCID 15956309HCID 15956309, compound

Procedure

In a manner analogous to the procedure described for Example 23, 8-[2-(3-aminophenyl)ethyl]-2-chloro-5,11-dihydro-11-ethyl-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one (0.15 g, 0.37 mmol) was diazotized and treated with sodium iodide to provide 9 mg of the pure product, m.p. 143°-145° C. (petroleum ether).

Sources & evidence

ORD record: ord-1d78ec31bd2846b8987fd4d1e17c95fc
Source dataset: uspto-grants-1998_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05705499

Reaction notes

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