Hydrochloric Acid → HCID 53959486, compound

HRID 725315Notes

Reaction equation

HRID 725315 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([N+:14]([O-:16])=[O:15])[C:12]=1[OH:13])[CH:5]=[CH:6][C:7]([OH:9])=[O:8].Cl.[CH:18](OC(C)C)(C)C>CO>[OH:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([N+:14]([O-:16])=[O:15])[C:12]=1[OH:13])[CH:5]=[CH:6][C:7]([O:9][CH3:18])=[O:8]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 7914Diisopropyl EtherHCID 54432225HCID 54432225, compound

Product 1

HCID 53959486HCID 53959486, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2.25 g of 3,4-dihydroxy-5-nitrocinnamic acid are dissolved in 50 ml of methanol and hydrochloric acid gas is introduced into this solution for 10 minutes. After 1 hour 50 ml of isopropyl ether are added thereto, and the separated precipitate is filtered under suction and washed with isopropyl ether. After recrystallization from methanol/ether there is obtained methyl 3,4-dihydroxy-5-nitrocinnamate in the form of yellow crystals of m.p. 186°-187°.

Workup

  1. filtrationthe separated precipitate is filtered under suction
  2. washwashed with isopropyl ether
  3. customAfter recrystallization from methanol/ether there

Sources & evidence

ORD record
ord-22fa475af239403cadc419cf58df5c90
Source dataset
uspto-grants-1998_01
Patent number
US05705703

Reaction notes

Loading…