Benzaldehyde → HCID 53689265, compound

HRID 727991Notes

Reaction equation

HRID 727991 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9]([C:12]1[CH:17]=[CH:16][C:15]([S:18]([NH2:21])(=[O:20])=[O:19])=[CH:14][CH:13]=1)([OH:11])=[O:10].CC1C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[CH:1](=[N:21][S:18]([C:15]1[CH:16]=[CH:17][C:12]([C:9]([OH:11])=[O:10])=[CH:13][CH:14]=1)(=[O:20])=[O:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 240BenzaldehydeHCID 6101p-Toluenesulfonic acidHCID 8739Carzenide

Product 1

HCID 53689265HCID 53689265, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In the same manner as Example 2, 4.00 g (38 mmol) of benzaldehyde, 7.58 g (38 mmol) of 4-carboxybenzenesulfonamide and 20 mg of TsOH in 150 mL of toluene were heated for 36 hours to afford 7.40 g (71%) of SULF-4 as a light tan powder: IR (Nujol) 3800-2600 (br), 1685, 1600, 1283, 1155 cm-1 ; 1H NMR (DMSO-d6, TMS ext std)δ 9.05 (s, 1), 8.2-7.2 (m, 9).

Workup

  1. customto afford 7.40 g (71%) of SULF-4 as a light tan powder

Sources & evidence

ORD record
ord-6baf021cd9a045d4b85670e1254569f7
Source dataset
uspto-grants-1991_09
Patent number
US05047163

Reaction notes

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