反应详情

1.45 g (5 mmol) of 2-dipropylamino-8-(2-aminoethoxy)-1,2,3,4-tetrahydronaphthalene and 1.38 g (10 mmol) of potassium carbonate were initially introduced into 20 ml of toluene. 0.77 g (5.5 mmol) of diethylcarbamoyl chloride was then added dropwise, and the mixture was stirred for 2 h at +100° C. The mixture was then filtered and evaporated. The product was obtained by chromatography over silica gel 60, 40-63 μm, using diisopropyl ether/ethanol, 3:2.

1. filtrationThe mixture was then filtered
2. customevaporated
3. customThe product was obtained by chromatography over silica gel 60, 40-63 μm