反应详情

2-Nitro-4-(heptadecyloxycarbonyl)aniline (0.42 g) was added to cold nitrosyl-sulphuric acid (70 mg of sodium nitrite and 1.5 ml of 98% sulphuric acid) and stirred at 0°-5° C. for 1.5 hours. Urea (0.1 g) was added and then the resulting mixture was added to a cold solution of N-methyl-N-(2-hydroxycarbonylethyl)aniline in a 1:1 mixture of acetic and propionic acids (10 ml). Sodium acetate was added and the reaction mixture was stirred for 1 hour after which time it was diluted with water and filtered. The red solid was purified by chromatography to give red product (yield: 0.15 g; mass spec: M+, 610).

1. stirringthe reaction mixture was stirred for 1 hour after which time it
2. filtrationfiltered
3. customThe red solid was purified by chromatography
4. customto give red product (yield: 0.15 g; mass spec: M+, 610)