Triethylamine → HCID 14995019, compound

HRID 729039Notes

Reaction equation

HRID 729039 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].C(N(CC)CC)C.[N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][C:14]=1[CH2:23][O:24][C:25]1[CH:39]=[CH:38][C:28]([CH2:29][C:30]2[CH:31]=[C:32]([CH:35]=[CH:36][CH:37]=2)[CH2:33][OH:34])=[CH:27][CH:26]=1>ClCCl>[S:2]([O:34][CH2:33][C:32]1[CH:35]=[CH:36][CH:37]=[C:30]([CH2:29][C:28]2[CH:38]=[CH:39][C:25]([O:24][CH2:23][C:14]3[CH:15]=[CH:16][C:17]4[C:22](=[CH:21][CH:20]=[CH:19][CH:18]=4)[N:13]=3)=[CH:26][CH:27]=2)[CH:31]=1)(=[O:4])(=[O:3])[CH3:1]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 14995018HCID 14995018, compound

Product 1

HCID 14995019HCID 14995019, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

To methanesulfonyl chloride (0.002 mol) and triethylamine (0.002 mol) in dichloromethane (40 ml) at 0° C. is added 3-(4-(2-quinolinylmethyloxy)benzyl)benzyl alcohol (0.0018 mol) in dichloromethane (40 ml) dropwise. After 24 hours, the reaction mixture is washed with water, dried and evaporated to give 3-(4-(2-quinolinylmethyloxy)benzyl)benzyl alcohol mesylate.

Workup

  1. washthe reaction mixture is washed with water
  2. customdried
  3. customevaporated

Sources & evidence

ORD record
ord-5c58d14ece984d08837e7a813c86aa14
Source dataset
uspto-grants-1991_09
Patent number
US05051427

Reaction notes

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