Acetic Anhydride → Acetoacetic Acid

HRID 729050Notes

Reaction equation

HRID 729050 reaction equation
[CH2:1]([C:3]1[C:4](CO)=[C:5]([CH3:10])[C:6]([OH:9])=[CH:7][CH:8]=1)[OH:2].[C:13]([O:16][C:17](=[O:19])[CH3:18])(=[O:15])C.[O:20]1CCCC1>>[CH3:3][C:1]([CH2:18][C:17]([OH:16])=[O:19])=[O:2].[CH2:10]([C:5]1[C:6]([OH:9])=[C:7]([CH2:13][OH:15])[CH:8]=[C:3]([CH3:1])[CH:4]=1)[OH:20]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 8028TetrahydrofuranHCID 66674803HCID 66674803, compound

Product 2

HCID 96Acetoacetic AcidHCID 70392,6-Dimethylol-p-cresol

Procedure

The diacetate of 2,6-dimethylol-p-cresol (DMPC) was prepared by reacting 3.4 g of the dimethylol cresol with 4.8 g of acetic anhydride in the presence of 7.8 g of tetrahydrofuran.

Sources & evidence

ORD record
ord-81661e37b6144090937e1dd1cca5ab46
Source dataset
uspto-grants-1991_09
Patent number
US05051454

Reaction notes

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