HRID729115

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C1CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN1

HCID161532

Nocardamine

C27H48N6O9

结构：CC(=O)/C=C(/C)[O-].CC(=O)/C=C(/C)[O-].CC(=O)/C=C(/C)[O-].[Fe+3]

HCID5483663

未命名化合物

PRODUCTS

生成物

结构：O=C1CCC(=O)N([O-])CCCCCNC(=O)CCC(=O)N([O-])CCCCCNC(=O)CCC(=O)N([O-])CCCCCN1.[Fe+3]

HCID167864

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

A solution of 5.29 g (15 mmol) of iron(III) acetylacetonate in 300 ml of ethyl acetate is added to a suspension of 5.26 g (10 mmol) of desferrioxamine E in 500 ml of water, and the mixture is efficiently stirred for 5 hours at room temperature. The aqueous phase is then extracted repeatedly with ethyl acetate and then lyophilised to give ferrioxamine E.

WORKUP

后处理

extractionThe aqueous phase is then extracted repeatedly with ethyl acetate

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b167aa1c96c8495586d0e4834a016061
来源数据集: uspto-grants-1991_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05051523
来源说明: uspto-grants-1991_09

反应 SMILES

C/C(/[O-])=C/C(C)=O.C/C(/[O-])=C/C(C)=O.C/C(/[O-])=C/C(C)=O.[Fe+3:22].[CH2:23]1[CH2:61][CH2:60][N:59]([OH:62])[C:57](=[O:58])[CH2:56][CH2:55][C:53](=[O:54])[NH:52][CH2:51][CH2:50][CH2:49][CH2:48][CH2:47][N:46]([OH:63])[C:44](=[O:45])[CH2:43][CH2:42][C:40](=[O:41])[NH:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][N:33]([OH:64])[C:31](=[O:32])[CH2:30][CH2:29][C:27](=[O:28])[NH:26][CH2:25][CH2:24]1>C(OCC)(=O)C.O>[CH2:23]1[CH2:61][CH2:60][N:59]([O-:62])[C:57](=[O:58])[CH2:56][CH2:55][C:53](=[O:54])[NH:52][CH2:51][CH2:50][CH2:49][CH2:48][CH2:47][N:46]([O-:63])[C:44](=[O:45])[CH2:43][CH2:42][C:40](=[O:41])[NH:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][N:33]([O-:64])[C:31](=[O:32])[CH2:30][CH2:29][C:27](=[O:28])[NH:26][CH2:25][CH2:24]1.[Fe+3:22]