反应详情

A solution of EXAMPLE 22B (1.00 g, 2.59 mmol) in dioxane (20 mL) at room temperature was treated with 4N HCl in dioxane (19.4 mL, 77.7 mmol), stirred overnight. Solvent was removed under reduced pressure. The residue was further dried under vacuum and used for the next step without further purification.

1. customSolvent was removed under reduced pressure
2. customThe residue was further dried under vacuum
3. customused for the next step without further purification