反应详情

2,4-pentanedione (205.4 ml, 2.0 mol), acetone (100 ml), n-butyl bromide (54 ml, 0.5 mol) and potassium carbonate (34.55 g, 0.25 mol) were put in a reaction vessel, purged with nitrogen and refluxed for 48 hours. The generated solid was filtered, and the solvent was removed using an evaporator. Unreacted-2,4-pentanedione was then removed under reduced pressure using a diaphragm. Then, vacuum distillation was then used to obtain 3-n-butyl-2,4-pentanedione (43.25 g, yield 55%).

1. custompurged with nitrogen
2. temperaturerefluxed for 48 hours
3. filtrationThe generated solid was filtered
4. customthe solvent was removed
5. customan evaporator
6. customUnreacted-2,4-pentanedione was then removed under reduced pressure
7. distillationThen, vacuum distillation