反应详情

Add 6-methoxynaphthalene-2-ol (20 g, 114.8 mmol) to dimethylformamide (DMF, 250 mL) at ambient temperature followed by N-bromosuccinimide (NBS 21.5 g, 120 mmol) over a 30 minute period. After 45 minutes, dilute with water (800 n-L), collect and dry the precipitate to provide 25.5 g (87%) of 1-bromo-6-methoxy-naphthalen-2-ol.

1. customcollect
2. customdry the precipitate