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HRID733317

反应详情

EQUATION

反应方程式

HRID 733317 的结构方程式

REACTANTS

反应物

4
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O
HCID85083

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-

C10H17NO4

结构：C[C@H](O)CN
HCID7311736

(S)-1-Aminopropan-2-ol

C3H9NO

结构：ClCCCl.On1nnc2ccccc21
HCID86583742

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](O)CNC(=O)[C@@H]1CCCN1.Cl
HCID86603946

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

Compound I6 was prepared by EDC/HOBT-coupling of (S)-2-hydroxy-propylamine with pyrrolidine-1,2(S)-dicarboxylic acid 1-t-butyl ester (analogous to Step A of Example I4), followed by HCl-cleavage in dioxane (Step B of Example I5). The crude salt was used as such.