HCID 86615212, compound → HCID 86615213, compound

HRID 733754Notes

Reaction equation

HRID 733754 reaction equation
[Cl:1][C:2]1[C:7]2[CH:8]=[C:9]([CH3:12])[N:10]([CH3:11])[C:6]=2[C:5]([C:13]([O:15]C)=[O:14])=[CH:4][N:3]=1>Cl>[ClH:1].[Cl:1][C:2]1[C:7]2[CH:8]=[C:9]([CH3:12])[N:10]([CH3:11])[C:6]=2[C:5]([C:13]([OH:15])=[O:14])=[CH:4][N:3]=1

Participants

3

Reactant 1

HCID 86615212HCID 86615212, compound

Product 1

HCID 86615213HCID 86615213, compoundYield 193.5%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of methyl 4-chloro-1,2-dimethyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylate (1.027 g) in 5N hydrochloric acid was heated under microwave conditions at 120° C. for one and a half hours, then evaporated to dryness to afford the title compound as a white solid 1.087 g.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-3ec97bda62d342d5b80fd44f2b33b3c4
Source dataset
uspto-grants-2009_09
Patent number
US07589206B2

Reaction notes

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