Methylamine → 6-Chloro-N-methylnicotinamide

HRID 734345Notes

Reaction equation

[CH3:1][NH2:2].[Cl:3][C:4]1[CH:12]=[CH:11][C:7]([C:8](O)=[O:9])=[CH:6][N:5]=1>>[Cl:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH:2][CH3:1])=[O:9])=[CH:6][N:5]=1

Participants

Reactant 2

HCID 6329Methylamine

HCID 792226-Chloronicotinic acid

Product 1

HCID 123642306-Chloro-N-methylnicotinamide

Procedure

The title compound (D42) was prepared from methylamine and 6-chloronicotinic acid according to the procedure described for Description 35.

Sources & evidence

ORD record: ord-3667e001d60c45c5b16771768a88c379
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07592347B2

Reaction notes

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